Mitchell scores 32, Garland adds 20 in return
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Cavaliers vs. Pacers odds, prediction: 2025 NBA picks for Friday, November 21 from proven model
Tipoff is set for 7 p.m. ET in Cleveland. Cleveland is a 13.5-point road favorite in the latest Cavaliers vs. Pacers odds, while the over/under is 238.5. Before making any Pacers vs. Cavaliers picks, check out the NBA predictions and betting advice from the SportsLine Projection Model.
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How to watch the Indiana Pacers vs. Cleveland Cavaliers game tonight: Time, TV Channel, Breakdown
After a disappointing loss to the Rockets, the Cavaliers host their third NBA Cup game against a division rival.
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How to watch Cavaliers vs. Pacers NBA game tonight on Prime Video: Start time, free live stream
Group play in the 2025-’26 NBA Cup continues Friday night with a matchup between the Cleveland Cavaliers and Indiana Pacers at Rocket Arena.
The Indiana Pacers and Cleveland Cavaliers meet Friday at Rocket Arena in Cleveland, Ohio. Tip-off is scheduled for 7 p.m. ET.
Indiana's defense will be dominated by Donovan Mitchell tonight, as our Pacers vs. Cavaliers picks, odds & expert predictions for Friday, November 21 explain.