A shaky hand, a racing heart, a wave of dread; alcohol withdrawal can feel like your body has turned against you. For many ...

Scripps Research scientists have found that LY2444296 - a compound that selectively blocks the kappa opioid receptor (KOP) - may reduce drinking in cases of alcohol dependence in animal studies. The ...

Researchers at the Ernest Gallo Clinic and Research Center at the University of California, San Francisco (UCSF), and Pfizer Inc., have determined that two new compounds may be effective in treating ...

Researchers for Scripps Research Institute and Eli Lilly have found that a compound called MTIP blocks a brain chemical, triggering a response that can stop excessive drinking, reduce the effects of a ...

The 2019 National Survey on Drug Use and Health reported that 14.5 million people ages 12 and older have alcohol use disorder, or AUD. This represents 5.3% of that population, according to the ...

Alcohol-related stimuli can trigger relapse of alcohol-seeking behaviors even after extended periods of abstinence. Extinction of such stimuli can reduce their impact on relapse; however, the ...