This is a preview. Log in through your library . Abstract The epithelial Na⁺ channel (ENaC) in the aldosterone-sensitive distal nephron (ASDN) is under negative-feedback regulation by the ...

The mechanism of increased adrenal sensitivity to angiotensin II during the aldosterone response to sodium restriction was investigated in the rat. Sodium restriction for 36 hr markedly increased the ...

Lorundrostat, a drug that blocks aldosterone production from the adrenal glands, showed significant and lasting reductions in blood pressure in 1,083 patients with uncontrolled or resistant ...

What if there were a straightforward and relatively inexpensive way to lower the incidence of heart failure (HF), renal disease, stroke, and cognitive impairment? Cardiologist Bertram Pitt, MD, said ...

Both the cause and a potential cure for the most common identifiable and specifically treatable cause of hypertension – aldosterone-producing adenomas (APAs) – have been revealed by researchers from ...

Please provide your email address to receive an email when new articles are posted on . Dysregulated aldosterone production, sometimes driven by obesity, can cause hypertension. Targeted therapies ...

Exercise cannot reduce a sodium-retaining hormone, aldosterone, which is known to potentially cause hypertension in African Americans. Many African Americans develop the salt-sensitive form of ...

Exercise cannot reduce a sodium-retaining hormone in African Americans known to potentially cause hypertension, found Michael D. Brown, Ph.D., the senior author of a study in the September issue of ...