Mutations in the BRCA1 gene that are either inherited (germline) or acquired (somatic) might not be key to the initiation of prostate cancer, as previously thought, suggests the first study of its ...

A common oral bacterium tied to gum disease may help spark and fuel breast cancer, according to new research. Scientists ...

Prostate cancer screening plans could be scaled back even further, despite growing calls for more testing to be rolled out.

The BRCA1 gene is located on the long arm of chromosome 17, at position 17q21. The gene spans around 100 kilobases and codes for a protein containing 1863 amino acids. Mutations or alterations that ...

A new study led by The University of Texas Health Science Center at San Antonio (UT Health San Antonio) is shedding light on a novel role of breast cancer gene 1 (BRCA1) in tumor suppression.

Ovarian cancer is the first in mortalities among gynecologic cancers in the United States, often due to late diagnosis and/or acquired platinum-resistant recurrences. This study investigates whether ...

When it was discovered by researchers in 1994, the BRCA1 gene was hailed as a landmark achievement not just in breast cancer prevention but in medicine in general. Its discovery led to the development ...

In women who have both breast cancer and the BRCA1 mutation, having surgery to remove the ovaries can significantly lower their risk of dying from the disease, suggests a new study published in the ...

The full name of the BRCA1 gene is “breast cancer 1, early onset,” and it codes for a tumor suppressor protein. Tumor suppressor proteins help repair DNA that has become damaged in order to ensure the ...

Breast cancer survivor Christina Applegate announced that she had her ovaries and fallopian tubes removed because she has the BRCA1 mutation — should you get tested? In 2008, Christina Applegate was ...