Researchers have taken a big step forward in the quest to regenerate the pancreatic beta-cells damaged by type 1 diabetes. Using FDA-approved drugs usually given to patients with rare cancers, they ...

Scientists have created a live-cell DNA sensor that reveals how damage appears and disappears inside living cells, capturing ...

A breakthrough live-cell sensor makes DNA repair visible as it happens, unlocking new possibilities in biology and medicine.

New live-cell DNA damage sensor lets scientists watch repair unfold in real time, potentially opening doors for cancer and aging research.

In a clinical trial led by University of Toronto researchers, an allogeneic stem cell–derived islet therapy (zimislecel) restored insulin production and ended severe hypoglycemia in adults with type 1 ...

In a recent study published in Nature Communications, researchers used a murine model to demonstrate that functional excision of murine phosphatidylinositol transfer protein alpha (PITPNA) impaired ...

Beta cells (marked in green) in the pancreas are organized in structures termed islets. In most adults, it was found that a subset become senescent and display the marker p16, shown here in red. The ...

Activating the GPR133 receptor with a small molecule can rebuild bone from within, offering a new direction for osteoporosis ...