A northern blot is a laboratory method used to detect specific RNA molecules among a mixture of RNA. Northern blotting can be used to analyze a sample of RNA from a particular tissue or cell type in ...

Probes are short, single-stranded chains of nucleic acid that seek out and latch themselves to a complementary sequence of nucleic acids, often buried anonymously in a much larger section of DNA/RNA.

In the early 1970s, Edwin Southern, a young investigator with Peter Walker's group in Edinburgh (University of Edinburgh) was deeply immersed in the problem of characterizing the two 5S ribosomal RNA ...