Efficient T-cell engineering is crucial for the success of CAR T-cell therapy research, but it requires multiple labor-intensive steps, including T-cell isolation, activation, and transduction.

Viruses are effective tools for delivering genetic material into cells, and scientists have taken advantage of viral transduction in numerous ways, such as constructing chimeric antigen receptor (CAR) ...

IB [email protected] of Chicago School of Medicine achieves first-ever automated 3-in-1 TCR-T manufacturing on Terumo Blood and Cell Technologies Quantum Flex Bioreactor ...

Combining micropillar deflection analysis, atomic force microscopy, and immunofluorescence staining provides a method for ...

Deciphering Cellular Networks from Gene Expression Data, Phosflow Assays & Pathogens Signaling networks within cells play a role in virtually every process from differentiation and proliferation to ...

Mitochondria are primarily known as the powerhouse of the cell. However, these cellular organelles are required not only for providing energy: Professor Konstanze Winklhofer and her group at the ...

Z. Zhong, Z.L. Wen, J.E. Darnell, Jr., "STAT3-a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6," Science, 264:95-8, 1994. (Cited in ...

Mitochondria, the “powerhouses of the cell,” are vital cellular organelles that govern energy metabolism, maintain redox ...

New research reveals that the loss of a single ion channel, TRPM1, is enough to produce persistent rhythmic oscillations in ...