PKM2 acts like a switch for cellular energy, directly determining whether cancer cells can rapidly generate energy and biosynthetic precursors to support their continued growth. Using a driving ...

Neoantigens are unique markers that distinguish only cancer cells. By adding B cell reactivity, cancer vaccines can move ...

Impact of multimodal, multidisciplinary care on clinical outcomes in patients with breast cancer and leptomeningeal carcinomatosis. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I ...

Mathematicians uncover a method to control cellular noise, offering a new way to prevent cancer cells from surviving and ...

Immune cells (macrophages) capable of combating cancer exist within tumors in the human body, but they are unable to fulfill ...

Ceralasertib in combination with Imfinzi (durvalumab) did not meet the primary endpoint of overall survival (OS) in the phase ...

Cirtuvivint is a selective pan-CLK, pan-DYRK inhibitor that modulates alternative RNA splicing, including transcripts involved in oncogenic pathways. Preclinical studies have shown that CLK/DYRK ...

In an era where precision medicine is redefining patient outcomes, cell separation technologies—encompassing the isolation of ...