San Francisco 49ers running back Christian McCaffrey rushes for a 12-yard gain against the Arizona Cardinals. Cleveland ...

San Francisco 49ers running back Christian McCaffrey scores his third touchdown of the game against the Arizona Cardinals ...

San Francisco QB Brock Purdy delivered a 9-yard touchdown pass to RB Christian McCaffrey in the team's Week 11 matchup ...

San Francisco 49ers RB Christian McCaffrey muscled his way into the end zone from one yard out during the 49ers Week 11 ...

San Francisco 49ers running back Christian McCaffrey, the NFL's leader in yards from scrimmage, could be in line to lay the ...

McCaffrey played great on Sunday, but he highlighted another running back after the 49ers’ win. Christian McCaffrey had 201 combined rushing and receiving yards in a win against the Falcons. McCaffrey ...

SANTA CLARA, Calif. (AP) — For all the stars the San Francisco 49ers might have been missing, they still had Christian McCaffrey. That proved to be the difference against the Atlanta Falcons.

The Houston Texans, in the midst of their Week 8 win over the San Francisco 49ers, 26-15, the Texans defense wound up holding star running back Christian McCaffrey to his quietest outing of an ...

McCaffrey, who starred for the Panthers from 2017 until they traded him to 49ers in 2022, faces his old Carolina team on ...