Several possible mechanisms have been proposed, including microbes (bacteria, fungi, viruses), biofilm formation, staphylococcal superantigen (most often associated with CRSwNP), osteitis and ...

CRSwNP affects up to 4% of the general population, with approximately 40% having uncontrolled disease. In Japan, about 200,000 people with chronic sinusitis are subject to surgery due to nasal polyps.

Nucala (mepolizumab), has been approved in China for treating adults with chronic rhinosinusitis with nasal polyps (CRSwNP), a condition affecting 30 million people in the country. This approval ...