Our brain's reward system processes and reinforces pleasurable experiences, motivating us to seek out and engage in rewarding ...

Dopamine, a chemical that sends messages between different parts of the brain and body, plays a key role in a variety of diseases and behaviors by interacting with receptors on cells. But despite ...

New research shows that the same dopamine receptor mechanism responsible for drug addiction also governs the natural decline in motivation when we repeat rewarding behaviors.

Not everyone with ADHD responds to stimulants like Ritalin, which increase dopamine levels in the brain. Now, new research suggests the drug’s effectiveness is less about the amount of dopamine it ...

Mount Sinai researchers have discovered distinct roles for two dopamine receptors located on nerve cells within the portion of the brain that controls approach vs. avoidance behavior. These receptors ...

Until recently, it has largely been assumed that G protein-coupled receptors (GPCRs) function as monomeric entities. However, over the past few years, we and others have documented that GPCRs can form ...

The dopamine D2 receptor has a previously unobserved role in modulating Wnt expression and control of cell proliferation, according to a new study from the George Washington University (GW) and the ...

December 6, 2007 -- A genetic polymorphism that reduces dopamine receptor density has been linked to a decreased ability to learn from errors. The German study, published in the December 7 issue of ...

Risk-taking, by definition, defies logic. Reason can’t explain why people do unpredictable things — like betting on blackjack or jumping out of planes — for little or, sometimes, no reward at all.

It seems preposterous that thrill seeker James Bond would have too few of anything, but new research suggests he may have a deficit of dopamine receptors. Earlier work has suggested that a propensity ...

Dopamine agonists are a form of drug that treats conditions such as Parkinson’s disease. Dopamine agonists imitate dopamine, which is a chemical that is important for various physical and mental ...