Circumstantial evidence for a dopaminergic locus of individual differences in cognition comes from pharmacological studies. If dopamine modulates cognitive function, it should be possible to improve ...

Parkinson's disease is a degenerative disorder of the central nervous system that is characterized by tremors, rigidity, slowness of movement, and difficulty walking. It is caused by loss of the ...

A new organoid model of the dopaminergic system sheds lights on its intricate functionality and potential implications for Parkinson’s disease. The model, developed by the group of Jürgen Knoblich at ...

As many as seven to 10 million people in the world are thought to live with Parkinson's disease (PD). Being the second most common neurodegenerative disease, PD severely affects patients' quality of ...

In a recent study published in Nature Neuroscience, a group of researchers explored how the cerebellum directly affects dopamine release in the substantia nigra compacta (SNc). While the cerebellum's ...

This Journal feature begins with a case vignette that includes a therapeutic recommendation. A discussion of the clinical problem and the mechanism of benefit of this form of therapy follows. Major ...

Researchers have discovered a type of "cellular bilingualism" -- a phenomenon that allows a single neuron to use two different methods of communication to exchange information. A team of researchers ...