Appropriate organization of three germ layers—endoderm, mesoderm and ectoderm—during gastrulation is essential for a developing embryo. Mechanistic studies on the morphogenesis of embryos in ...

(Philadelphia, PA) – Researchers at the Lewis Katz School of Medicine at Temple University have discovered that the Hippo signaling effector YAP1 is a master regulator of Nodal signaling in human ...

Using a method called CEL-Seq that can spy on the activity of every gene within a cell at once, Technion Associate Professor Itai Yanai and his colleagues now provide compelling evidence that the ...

Uniting three different parameters in single cells taken from mouse embryos reveals more about how foundational cell identities are established in early development The first single-cell multi-omics ...

Engineers and a pediatric surgeon have joined forces to discover that physical forces like pressure and tension affect the development of limbs in embryos -- research that could someday be used to ...

An undifferentiated cell found in a differentiated tissue that can renew itself and (with limitations) differentiate to yield the specialized cell types of the tissue from which it originated. A ...

A study published today (September 11) in Nature Ecology & Evolution suggests that instead of two distinct germ layers, cnidarians may indeed have three. The authors show that the mesendoderm of the ...