Challenging the long-standing belief that fibroblasts produce skin collagen, researchers have investigated collagen formation in the 'glass-skinned' amphibian axolotl and other vertebrates. They ...

A study provides insights into the diversity of cancer-associated fibroblasts in white and black skin cancer and describes their different immunomodulatory roles in the tumor environment. The results ...

The skin consists of two primary layers. The epidermis, the outermost layer, is predominantly made up of keratinocytes, while the deeper dermis contains blood vessels, nerves, and structural proteins ...

A new study in Cell Reports offers fresh evidence that fibroblasts actively shape inflammatory environments in skin disease. Using single-cell RNA sequencing and multiplexed error-robust fluorescence ...

A study at MedUni Vienna's Department of Dermatology provides insights into the diversity of cancer-associated fibroblasts in white and black skin cancer and describes their different immunomodulatory ...

L uis Garza, a physician-scientist at Johns Hopkins University School of Medicine for over a decade, noticed a common issue when treating people with limb amputations at his clinic. They often had ...

A cut that would close in days on a 25-year-old can linger for weeks on a 75-year-old, and the usual explanations (thinner skin, poorer blood flow, weaker immunity) only tell part of the story.

Fibroblasts are specialized cells in connective tissues that play an important role in wound healing and tissue repair. They produce and organize the so-called extracellular matrix, a network of ...

Axolotl is an animal model widely used in dermatology research due to its transparent ‘glass skin.’ A study by researchers from Okayama University, Japan, discovered that healthy collagen fibers, ...