Modern bioassays tend to fall under three common modalities: colorimetric, luminometric or fluorometric. Colorimetric assays record the amount of light absorbed by a reporter compound. This absorbance ...

In recent years, fluorescence quenching microscopy (FQM) 1-3 has emerged as a viable technique that allows for the swift, cost-effective, and accurate imaging of two-dimensional (2D) materials like ...

a. MRA helps resolve the dense actin filaments with SIM imaging. b. MRA helps resolve the mitochondrial cristae cluster with LiveSR imaging. c. SecMRA helps better section the ER tubule structure. d.

Biologists are very interested in how proteins, lipids and other compounds are organized and interact in systems. Very few organizational details can be gained by using standard transmission-based ...

A new two-photon fluorescence microscope developed at UC Davis can capture high-speed images of neural activity at cellular resolution thanks to a new adaptive sampling scheme and line illumination.

Light-sheet fluorescence microscopy (LSFM), with its innovative design of selective plane illumination and orthogonal detection optics, significantly reduces phototoxicity and photobleaching inherent ...

Microscopy is an imaging technique that enables us to see a world that would otherwise be invisible to us. Once upon a time, visualizing cells, microbes and other entities not perceptible to the naked ...

What does the inside of a cell really look like? In the past, standard microscopes were limited in how well they could answer this question. Now, researchers have succeeded in developing a microscope ...

The core mechanism involves labeling a target molecule, substrate, or probe with a fluorophore. Upon excitation, the fluorophore emits a signal that is proportional to the presence or activity of the ...

The Gregorio Weber Award for Excellence in Fluorescence Theory and Applications is an annual award which honors and recognizes distinguished individuals who have made original and significant ...