Compared with viral vectors, non-viral delivery vectors are easier to scale up and have the ability to solve the most critical safety issues. Thanks to the LNP-mRNA vaccine that came to the fore ...

More complex and challenging compounds require a more tailored approach to formulation strategies. Increasingly challenging and complex molecules entering the development pipeline are changing the way ...

To optimize the final formulation for a drug, it must meet many criteria beyond producing a safe and effective product. For example, it must be stable and amenable to various manufacturing steps, such ...

Formulation scientists are behind the conversion of active pharmaceutical ingredients (API) into stable, bioavailable, and commercially viable dosage forms, rarely a simple process. Image Credit: ...

Developers need to consider key challenges when approaching accelerated formulation strategies to ensure success. Accelerated formulation strategies can aid with cost and time-efficiencies in drug ...

Proteolysis-targeting chimeras (PROTACs), particularly those incorporating the von Hippel–Lindau (VHL) E3 ligase ligand, present significant physicochemical challenges due to their large molecular ...