G-protein coupled receptors (GPCRs) are proteins triggered by ligands (protein-binding chemicals) from outside cells to ...

Heterotrimeric G proteins, comprising Gα, Gβ and Gγ subunits, are central to the transduction of extracellular signals into precise intracellular responses in plants. These proteins not only regulate ...

UNC researchers discovered how a key step in cell signaling works by showing exactly how G proteins detach from receptors that many common medicines target. Scientists at the University of North ...

Regulators of G‐protein signalling (RGS) proteins are pivotal modulators of cellular communication owing to their capacity to fine‐tune signals propagated via G protein‐coupled receptors (GPCRs).

G protein-coupled receptors (GPCRs) are expressed on the surface of cells and regulate a range of important functions. Because they are involved in so many sensory and physiological processes, ...

The design of new calcium channels, built bottom-up from scratch, was reported last week in Nature. Subscribe to our newsletter for the latest sci-tech news updates. Ion channels generate electrical ...

Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...

A large, multi-institution study led by a Brown University physician-scientist could have important implications for the development of new classes of cancer therapeutics.

Opioid receptors are a subset of G protein–coupled receptors (GPCRs). These membrane proteins transmit signals into the cell ...

Researchers at LMU have uncovered how ribosomes, the cell’s protein builders, also act as early warning sensors when ...

A protein essential to the human body for managing energy and regulating appetite relies on a partner protein, according to ...