A number of membrane proteins that are present on the cell membrane control external and internal material transportation, cell protection and signal transmission. The diversity of functions of ...
LA JOLLA, CA – July 12, 2012 –Readers of the top-ranked scientific journals Science and Nature might have noticed a recent wave of articles, most recently in the July 13, 2012 issue of Science, with ...
UNC researchers discovered how a key step in cell signaling works by showing exactly how G proteins detach from receptors ...
DISCOVERY OF THE ATOMIC STRUCTURE OF A LIGAND-FREE G PROTEIN-COUPLED RECEPTOR (GPCR) WILL HELP DESIGN MORE EFFECTIVE DRUGS NEW YORK (February 26, 2013) — A research team at Weill Cornell Medical ...
Cell behaviour is regulated by myriad external stimuli that act through specialized receptor proteins at the cell surface. G-protein-coupled receptors (GPCRs) are the largest family of receptors and ...
Versatility, thy name is G protein–coupled receptor (GPCR). Besides responding to diverse extracellular stimuli, GPCRs initiate diverse signaling reactions. Indeed, most GPCRs are multivalent. That is ...
Yeast cells are widely used to study G protein-coupled receptors (GPCRs), a large group of cell surface proteins in humans. However, several of these proteins lose their function when introduced into ...
GPCRs (G-protein-coupled receptors) represent the largest family of membrane receptors currently targeted by approved drugs. It is estimated that approximately 700 approved drugs target GPCRs ...
A group of researchers has identified the cause of a 'short-circuit' in cellular pathways, a discovery that sheds new light on the genesis of a number of human diseases and could lead to development ...
Scientists at Scripps Research have comprehensively mapped how a key class of proteins within cells regulates signals coming in from cell surface receptors. The study reveals, among other things, that ...
In a new study, a multinational research team led by Dr. Adnan Sljoka (RIKEN) and Prof. Akio Kitao (Tokyo Tech), in collaboration with Prof. Scott Prosser (University of Toronto), has carried out ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results
Feedback