Humans have it. So does Drosophila. But not yeast. That "it" is a small pause at the start of gene activity—a brief molecular ...

An international team, including researchers from HSE University, has created the first comprehensive map of ...

DNA sequences that regulate expression of the insulin gene are located within a region spanning ~400 bp that flank the transcription start site. This region, the insulin promoter, contains a number of ...

Scientists have created the first comprehensive map of DNA quadruplexes, fleeting knot-like structures that play an outsized ...

A newly discovered promoter element "start" points to a shared regulatory syntax for controlling transcription initiation in ...

A split-second stall at the start of genes may explain how complex animals evolved, according to the Cornell Chronicle. Researchers found that a brief “pause” in gene activity grew stronger and more ...

Around 98.5% of human DNA is non-coding, meaning it doesn’t get copied to make proteins. A new study has connected many of these non-coding regions to the genes they affect and laid out guidelines for ...

A recent study in genetic control elements revealed around 11,000 gene regulators active in every cell type, also known as housekeeping cis-regulatory elements (HK-CREs). These elements are vital in ...

DNA methylation is a key epigenome component that helps dictate how genes are expressed, contributing to normal cell and tissue differentiation during development, as well as the process of biological ...

This study identifies around 11,000 housekeeping cis-regulatory elements (HK-CREs), revealing their important role in cellular stability and potential tumor suppression capability across diverse ...