The most comprehensive map of the developing human thymus sheds light on how immune responses are built and maintained at early life, with implications for understanding and treating immunodeficiency, ...

CD8 + cytotoxic T lymphocytes (CTLs) serve as central effectors in cancer immunotherapy by directly eliminating tumor cells. However, current clinical therapies face significant limitations. These ...

Why does the same virus barely faze one person while sending another to the hospital? New research shows the answer lies in a molecular record etched into our immune cells by both our genes and our ...

An initiative partly funded by the Wellcome Trust Sanger Institute in the UK has moved further towards its goal of producing a 'human cell atlas' (HCA) to map every cell type in the human body.

A new method to keep human lymph node tissue alive and functioning outside the body for several days could give researchers a much clearer view of how our immune system responds to infections, ...

Study reveals how our immune system transforms across a lifetime—unlocking the potential for predicting disease risk and optimizing health before symptoms appear. Resource: Integrating single-cell RNA ...

How does the same infection, say the flu or a cold, give some people mild symptoms and leave others suffering? Why do people develop autoimmune diseases? And will we ever be able to predict when—and ...

Human peadiatric thymus image from the IBEX protein multiplex (44 proteins on the same image) platform. Thymic epithelial cells are labeled with DEC205 (cyan), pan-cytokeratin (purple), keratin 5 (red ...