Isocitrate dehydrogenase (IDH) catalyzes the conversion of isocitrate to α-ketoglutarate in the Krebs (citric acid) cycle. This enzymatic pathway is associated with various molecular processes ...
Physicians and cancer researchers in Heidelberg and Mannheim have for the first time carried out a clinical trial to test a cancer vaccine candidate that targets a specific mutation in the isocitrate ...
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