Medline shares surged in their trading debut Wednesday, after the medical supply company raised $6.26 billion in one of the biggest initial public offerings in recent years.

On October 1, Renaissance Capital released its Q3 2025 US IPO market review. The third quarter marked the biggest quarter for IPOs since 2021.

After a shaky start to the year due to uncertainty about the Trump administration's tariffs and stock market volatility in the spring, activity in the initial public offering (IPO) market picked up in the third quarter of 2025.

Explore the complexities of Indian IPOs since 2021, highlighting trends, risks, and the shift from investment to short-term trading.

Medline shares began trading under the ticker “MDLN” Wednesday in the biggest IPO since 2021.