Inositol trisphosphate receptors (IP3Rs) are pivotal Ca²⁺ channels embedded in the membrane of the endoplasmic reticulum. Their activation by inositol 1,4,5-trisphosphate (IP3) and Ca²⁺ gives rise to ...
Inositol 1,4,5-trisphosphate receptors (IP₃Rs) initiate a diverse array of physiological responses by carefully orchestrating intracellular calcium (Ca2+) signals in response to various external cues.