Figure 1: Integrin beta-1 is increased in activated HSCs and required for phenotype and function. Figure 2: Integrin beta-1 is required for multiple pro-fibrotic features in activated HSCs. Figure 3: ...

Homomeric and heteromeric interactions between the αIIb and β3 transmembrane domains are involved in the regulation of integrin αIIbβ3 function. These domains appear to interact in the inactivated ...

Researchers at Tampere University, Finland, have published new results in collaboration with an international research network that help to understand the biological phenomena mediated by cell ...

Recruitment of receptor proteins to lipid rafts has been proposed as an important mechanism to regulate their cellular function. In particular, rafts have been implicated in regulation of ...

Protein evolution occurs slowly via small incremental mutations—usually. However, dramatic changes can happen: for instance, a fragment of one protein getting copied into the middle of another. While ...

WALTHAM, Mass.--(BUSINESS WIRE)--Morphic Therapeutic (Morphic), a biotechnology company developing oral integrin therapies, announced today that it has entered into a research and development ...

The prognostic value of cognition in patients with glioblastoma multiforme. This is an ASCO Meeting Abstract from the 2013 ASCO Annual Meeting I. This abstract does not include a full text component.

Johns Hopkins University biologists have found that a protein that plays a key role in the lives of stem cells can bolster the growth of damaged muscle tissue, a step that could potentially contribute ...

Morphic and Janssen have entered into a research and development collaboration to discover and develop novel integrin therapeutics. Morphic Therapeutic and Janssen have entered into a research and ...

Biologists have found that a protein that plays a key role in the lives of stem cells can bolster the growth of damaged muscle tissue, a step that could contribute to treatments for muscle ...