Johns Hopkins University biologists have found that a protein that plays a key role in the lives of stem cells can bolster the growth of damaged muscle tissue, a step that could potentially contribute ...

In the present study, we aimed to investigate the functional significance of CRP in the acquisition of the adhesive phenotype of breast epithelial cells upon inflammatory environment. Here, we show ...

Exploiting stem cells for their restorative properties is the primary underlying goal of regenerative medicine. Now, researchers at Johns Hopkins have identified a protein that plays a vital role in ...

Integrin-associated protein (IAP), CD47, was first found in research that focused on integrin αvβ3. This research found that CD47 was to be associated in cis with integrin αvβ3 on the cell membrane.

High levels of IB6 are often found in NSCLC, making it a good target for treatment. A preclinical study found that in lung cancer, IB6 was correlated with interleukin-8 levels and promoted cancer cell ...

As we age, the function and regenerative abilities of skeletal muscles deteriorate, which means it is difficult for the elderly to recover from injury or surgery. New work from Carnegie's Michelle ...

Protein evolution occurs slowly via small incremental mutations—usually. However, dramatic changes can happen: for instance, a fragment of one protein getting copied into the middle of another. While ...

Mary Zutter and colleagues, at Vanderbilt University Medical Center, Nashville, have generated data that lead them to suggest that decreased expression of the protein alpha-2 integrin is predictive of ...

This is a preview. Log in through your library . Abstract Thiols affect a variety of cell functions, an effect known as redox regulation. We show here that treatment (1-2 h) of cells with 0.1-5 mM ...