They were randomized to flexible doses of Stalevo or levodopa/carbidopa IR administered four-times daily on a q3.5 h schedule with a target dose of approximately 400 mg levodopa per day.

They help manage "wearing off" episodes at the end of levodopa doses, which occur when Parkinson's symptoms, such as muscle ...

Monitor for 2 weeks or until 24hrs after last dose of linezolid or IV methylene blue, whichever comes first. Avoid alcohol. Levodopa, amantadine may increase CNS toxicity. Caution with drugs that ...

Monitor for 2 weeks or until 24hrs after last dose of linezolid or IV methylene blue, whichever comes first. Avoid alcohol. Levodopa, amantadine may increase CNS toxicity. Caution with drugs that ...

In addition, the patients required reduced levodopa doses compared with baseline over the 3-year period. Adverse events were exhibited by 20 patients following surgery and 14 of these individuals ...

Polish drugmaker Celon Pharma (WSE: CLN) has announced positive results from a Phase II trial of CPL’36, an experimental oral ...

Researchers have been working to see how much of a role the human microbiome could be playing in the varying responses people experience to levodopa. Receive a weekly dose of discovery in your inbox!

notably Mitsubishi Tanabe Pharma’s ND-0612 – a liquid fixed dose combination of levodopa and carbidopa administered through a patch-pump or belt pump – which generated positive phase 3 ...

Celon Pharma’s PDE10A inhibitor has reduced involuntary movements in a phase 2 trial of individuals with Parkinson’s disease.

Table 1. Percentage of patients decreasing daily levodopa dose by 4–6 weeks after entacapone initiation in Phase III clinical trials as grouped by baseline daily levodopa dose and presence of ...