The sample throughput of high-sensitivity liquid chromatography-mass spectrometry (LC-MS) based proteomics analysis is restricted by the pressure limitations of LC and column hardware, with some ...

MALDI remains a powerful tool for analyzing large biomolecules with minimal fragmentation. In this process, peptides or proteins are co-crystallized with a matrix on a metal plate. A laser pulse ...

Can you provide an overview of your recent initiatives, particularly your spinout company and research institute, and how they relate to your academic work? We established the Parallel Squared ...

Over the past several years, proteomics has seen a surge in interest among life scientists and the biopharma industry, akin to the previous rise of genomics. It is becoming more evident that ...

Matthias Trost (left) is a Professor at Newcastle University (UK) with a lab comprising three focuses: method development for proteomics, the application of mass spectrometry in drug discovery and the ...

Mass spectrometry–based proteomics encompasses a suite of analytical approaches designed to identify, characterise and quantify the full complement of proteins in biological samples. Central to these ...

Researchers use mass spectrometry-based methods for single-cell proteomics, where they can identify and quantify thousands of proteins, proteoforms, and post-translational modifications within each ...

Proteomics, which is generally defined as the characterization of the complete protein complement of a cell, tissue, or organism (a proteome), has moved to the forefront of "big science" now that the ...

Jianwei Shuai's team and Jiahuai Han's team at Xiamen University have developed a deep autoencoder-based data-independent acquisition data analysis software for protein mass spectrometry, which ...

Bruker Corporation today announced new advancements to enable Functional Proteomics 2.0 workflows on the timsOmni ™ mass spectrometer to enable disease researchers to move beyond canonical protein ...