Cancer-associated fibroblasts (CAFs) are crucial in melanoma metastasis, influencing tumor microenvironments and patient outcomes, especially in immunotherapy contexts. Single-cell RNA sequencing ...

Melanoma is a type of skin cancer that can spread rapidly to other areas. However, there are also slow-growing types that may develop over many years. Melanoma is not as common as other types of skin ...

A gene expression-based test identifies patients with primary cutaneous melanoma at a lower or higher risk for sentinel lymph ...

Investigators from Weill Cornell Medicine have discovered a defense mechanism that protects skin cancer cells from oxidative stress and helps them spread. The findings suggest a new drug target that ...

Institut Curie researchers have identified a sex-specific molecular pathway connecting E-cadherin loss, estrogen receptor-α (ERα), and GRPR, contributing significantly to increased melanoma metastasis ...

Aggressive cancer cells are masters of movement. When they spread through the body, they cause metastasis, which significantly reduces a person's chance of survival. For this spreading to take place, ...

A protein critical to melanoma cell metastasis has been discovered, offering strategies to impede cancer spread throughout the body. In a recent study, researchers from the Center for Genomic ...

Melanoma can spread to many tissues in your body including your brain. Treatment for melanoma that has spread to the brain usually focuses on prolonging life and reducing symptoms. Melanoma is the ...