How large, fully folded proteins can pass through cell membranes without destroying them has long been one of the open ...

The GLP-1 receptor, one of the most successful drug targets for the treatment of type 2 diabetes and obesity, is known to engage multiple intracellular signaling proteins. However, it remains less ...

Dynamic protein distribution within and across the plasma membrane is pivotal in regulating cell communication. However, rapid, high-density labeling methods for multiplexed live imaging across ...

Cell membrane proteins hide secret gateways that can be used to modify cell behavior. This has been demonstrated in a study led by the Hospital del Mar Research Institute and published in Nature ...

Cellular membrane proteins play important roles in cellular transport, signaling, and cell-to-cell communication. Malfunction in membrane proteins can lead to serious diseases, such as cancer. However ...

Membrane proteins and membrane lipids are essential partners in various biological processes, and elucidating their structures in a natural membrane environment is crucial for enhancing our ...

Located at the cellular interface, membrane proteins play critical regulatory roles in the signaling between a cell and its interacting environment, making them popular and ideal drug targets.

Scientists at UT Southwestern Medical Center, working with other U.S. researchers, have uncovered the structure of a key cell ...

Researchers at the University of Notre Dame and collaborators have discovered a key process in how the outer membrane of gram ...

In a study published in Analytical Chemistry, a research team led by Wang Junfeng from the Hefei Institutes of Physical Science of the Chinese Academy of Sciences has developed a novel immobilization ...