Analysis of specific DNA alterations in precision medicine of tumors is crucially important for molecular targeted treatments. Lung cancer is a prototypic example and one of the leading causes of ...

A key focus of research on pancreatic ductal adenocarcinoma (PDAC) is identifying new techniques to tailor gemcitabine and 5-fluorouracil treatments. Availability of tumor tissue is critical for the ...

Therapeutic implications of phosphoproteomics in molecular cancer diagnostics. Utility of [18F]FDG PET/CT in predicting pathological complete response to neoadjuvant therapy in breast cancer: A ...

LCM is principally used to dissect and collect samples from histological sections and cell cultures, down to one-cell level and even below. A typical downstream application is RNA or DNA isolation.

Understanding genomic variation in the context of cancer is paramount to identifying disease drivers and informing personalized treatment for patients. Tumor heterogeneity presents a challenge in ...