Monocytes, a special type of white blood cell, play an important role in the innate immune system and contribute to host defense in the blood by secreting large quantities of pro-inflammatory ...
Clonal hematopoiesis of indeterminate potential (CHIP) is a known risk factor for coronary artery disease, though its precise role in disease progression continues to emerge. This study leverages ...
Economic impact of progressive disease (PD) following frontline therapy in classical Hodgkin lymphoma (HL). This is an ASCO Meeting Abstract from the 2014 ASCO Annual Meeting I. This abstract does not ...
Adrenomedullin as an immunomodulator of CD14+MerTK+ circulating monocytes in liver failure syndromes
Adrenomedullin is increased in acute liver failure syndromes (ALF and ACLF), and AMBP1 is, on the contrary, reduced, mirroring the severity of the disease expressed by the SOFA score. ADM affects ...
Human umbilical vein endothelial cells (HUVECs) were seeded at 1 × 10 4 cells per cm 2 in six-well plates. Treatment with TNF-α (2.5, 5 or 10 ng/ml) or lipopolysaccharide (0.5, 1 or 5 μg/ml) treatment ...
Liver failure syndromes are characterized by a dysregulated immune response leading to immune paralysis. Adrenomedullin (ADM) is a potent vasodilator and immunoregulator. This study aimed to explore ...
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