The energy needs of neurons are prodigious—the brain makes up just a small percentage of the body, yet burns roughly 25 percent of its calories (Leonard et al., 2007). That hunger for energy requires ...
For many years now, scientists have relied on genetically engineered mouse models of Alzheimer disease (AD) to chart new course for treatment and diagnosis. The best known (and best studied) of these ...
Researchers have demonstrated that enhancing myelin renewal in the brains of transgenic APP/PS1 mouse models of Alzheimer's disease (AD) can improve their task-related hippocampal activity. "To the ...