The NFL is serving up a three-game Thanksgiving slate of NFL matchups in 2025, where we'll be treated to some high-stakes ...

The San Francisco 49ers lost defensive end Sam Okuayinonu in Monday's game to an ankle injury, and now he'll miss some time.

The Arizona Cardinals are back in action in Week 11, facing the San Francisco 49ers for the second time this season. The 6-4 ...

San Francisco 49ers edge rusher Nick Bosa and linebacker Fred Warner both suffered significant injuries earlier in the season ...

49ers defensive end Sam Okuayinonu did suffer an ankle injury early during San Francisco's "Monday Night Football" date ...

Quarterback Joe Burrow is set to make his long-awaited return for Cincinnati after nearly making the start last weekend ...

The Rams and 49ers released their final injury reports of Week 10, sharing updates on Puka Nacua, Darious Williams and Brock ...

The San Francisco 49ers' Week 10 injury report didn't have much good news for a handful of the team's starters.

The Indianapolis Colts and Houston Texans are concerned with their quarterbacks heading into their NFL Week 13 matchup.

ESPN NFL insider Jeremy Fowler provided an interesting update on Aiyuk's future in San Francisco. While he reports this saga ...

The New England Patriots will place left tackle Will Campbell on injured reserve and sign cornerback Miles Battle to the ...

Is Trey Benson playing this week? The Cardinals RB's practice window from IR is open. Here's the latest injury update.