Ataxia with oculomotor apraxia is an autosomal recessive inherited disease characterized by childhood onset of progressive cerebellar ataxia, oculomotor apraxia, and progressive motor peripheral ...

A defective response to DNA damage is observed in several human autosomal recessive ataxias with oculomotor apraxia, including ataxiatelangiectasia. We report that senataxin, defective in ataxia ...

The patient was a 67-year-old Japanese woman, who was born to consanguineous parents and attained normal developmental milestones during infancy. At ∼17 years old, she began falling frequently while ...

Autosomal recessive cerebellar ataxias (ARCAs) are rare and early-disabling neurodegenerative-movement disorders caused by dysfunction in the cerebellum. The most common form is Friedreich ataxia. A ...

Hamilton, ON (March 30, 2015) - Researchers from McMaster University and the Icahn School of Medicine at Mount Sinai, New York have discovered that a protein associated with neurodegenerative diseases ...

Isolated third cranial nerve palsies in head trauma patients can be the result of direct or indirect damage to the oculomotor nerve. They are usually associated with severe head trauma. We reported a ...

Ataxia with oculomotor apraxia is an autosomal recessive disease, originally described in Portuguese patients and later in Japanese patients. Symptoms first noticed appear between ages 1 and 16 years ...

New insight into the link between neurodegenerative disorders and inflammation has been gained by a new study that provides a framework to explore more fully the possibility that viral infection may ...

Researchers from McMaster University in Hamilton, Ontario, Canada and the Icahn School of Medicine at Mount Sinai, New York have discovered that a protein associated with neurodegenerative diseases ...