NEW YORK (Reuters Health) - Activation of delta opioid receptors inside cells is important for the relief of inflammatory pain, researchers report. "Most medicines targeting receptors are designed to ...

The group of researchers were the first to take snapshots of the moment naloxone reverses an opioid overdose in the brain.

The researchers captured eight unique structural models and 16 cryogenic electron microscopy maps of the receptor with both ...

Researchers at the Department of Infection and Immunity of the Luxembourg Institute of Health (LIH) have developed a novel molecule that binds to and blocks a previously unrecognized opioid receptor ...

Scientists have visualized for the first time how opioids such as loperamide and the antidote naloxone engage a key brain receptor, offering insight that could lead to better pain treatments.

To date, therapies for multiple sclerosis (MS) focus on modifying or suppressing the immune system rather than on remyelination. Recent findings have pointed to the κ-opioid receptor (KOR) as a ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 119, No. 16 (April 19, 2022), pp. 1-10 (10 pages) Allosteric modulators of G-protein-coupled receptors (GPCRs) ...

Drugs that target opioid receptors sometimes have severe side effects. Thousands of people around the world die every day from overdoses involving opioids such as fentanyl. Researchers have taken a ...