Method A. Sodium ALE (0.25 mmol) was dissolved in 10% aqueous acetic acid and the solution was frozen and lyophilized. The free carboxylic group of Resomer RG 502 H was activated by dissolving the ...

Purdue University researchers are developing and validating patent-pending poly (lactic-co-glycolic acid), or PLGA, nanoparticles modified with adenosine triphosphate, or ATP, to enhance immunotherapy ...

Active pharmaceutical ingredients (APIs), including both small molecules and biologic compounds, are often encapsulated in microspheres and nanoparticles. This encapsulation is utilized for specific ...

When designing a nanoparticle-enabled drug delivery system, many intersecting considerations must be taken into account, such as the target location of the drug payload, the method of delivery, uptake ...

Polymeric nanoparticles are nanoscale-sized objects constructed from polymers such as polyethylene glycol (PEG) or polylactide-co-glycolide (PLGA), with applications in the in vitro delivery of ...

A new nanoparticle made from the medical polymer PLGA and the blood protein albumin can carry higher doses of drugs and remain stable longer, offering improved delivery and fewer side effects. For ...