Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, progressive, multi-system, life-threatening disease, and diagnosing it early in the clinical course is essential for optimizing management ...

Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired, potentially life-threatening disorder linked to a specific gene. It can occur at any age but most often is diagnosed in young adults. PNH ...

A novel, single tube, multi-parameter 7-color immunophenotyping assay was developed to characterize PNH clones in blood leukocytes. Monocytes, eosinophils and basophils had the highest proportion of ...

A acquired deficiency in the PIGA gene alters red blood cells. Paroxysmal nocturnal hemoglobinuria results when these altered cells replicate. Medications can stop the breakdown of red blood cells and ...

Fewer than 50,000 people in the United States live with paroxysmal nocturnal hemoglobinuria (PNH). It’s a blood disease that impairs the production of red blood cells. PNH causes the destruction of ...