Scientists have re-created a pain pathway in the brain by growing four key clusters of human nerve cells in a dish. This laboratory model could be used to help explain certain pain syndromes, and ...

Osteoarthritis can be a debilitating disease, rendering regular movements painful. Researchers have now identified a signaling pathway that transmits this pain, with a study in mice finding that ...

Scientists from Tulane University and The University of Texas at Dallas have discovered a new way that nerve cells communicate – by releasing an enzyme outside the cell that switches on pain signaling ...

So when you touch a hot stove, the nerve endings in your fingers react instantly. But the ouch comes a split-second later, when that information finally reaches your brain. Well, now, scientists have ...

Researchers at Tulane University, with a team of colleagues from eight other universities, have discovered a new nerve cell signaling mechanism that could transform our understanding of pain and lead ...

In a new discovery, chronic pain has been shown to be physiologically different from acute pain and now scientists have the roadmap for how to target it. Researchers from the University of Aberdeen, ...

Researchers have discovered that a particular molecular signaling pathway plays an important role in producing osteoarthritis (OA) pain. Using a mouse model of painful osteoarthritis, they show that ...

Scientists have recreated a pathway that senses pain, using clusters of human nerve cells grown in a dish. Pain pathway in a dish could aid search for new analgesic drugs Scientists have re-created a ...