This new article publication from Acta Pharmaceutica Sinica B, discusses allosteric modulation of G protein-coupled receptors as a novel therapeutic strategy in neuropathic pain. Neuropathic pain is a ...

It’s not all in your head, but your expectations can sway your perception of pain intensity. Information about expectations — the driver of the placebo effect — travels from the cortex to groups of ...

Scientists created a model of the human pain pathway in a dish by connecting four separate brain organoids. The feat should help them understand sensory disorders like those affecting pain perception.

René Descartes gave a colorful description of the mechanism of pain in the 17th Century: "Particles" of fire set in motion a spot on the skin of the foot, and by means of a "delicate thread" they open ...