Janelia scientists and longtime collaborators Eric Betzig and Harald Hess will be inducted into the 2024 class of the National Inventors Hall of Fame for their invention of photoactivated localization ...

A decade ago, the Nobel Prize in Chemistry was awarded to a trio of researchers for the development of super-resolved fluorescence microscopy. The announcement at the time stated that the researchers’ ...

During organismal development, homeostasis, and disease, Dishevelled (Dvl) proteins act as key signaling factors in beta-catenin–dependent and beta-catenin–independent Wnt pathways. While their ...

Single-particle tracking photoactivated localization microscopy (sptPALM) is a technique to visualize the movement of individual proteins. While some of the shuttle components of the injectisome are ...

MINFLUX is a super-resolution microscopy protocol designed to improve the localizing of specific photon emitters in space. Developed in 2016 by a German team including super-resolution pioneer and ...

One method for visualizing dynamic biological processes is single particle tracking, a localization microscopy method. For this technique to be successful, several factors need to be considered, ...

Even those who maintain that super-resolution microscopy is a powerful tool of biological discovery have admitted that it may have a bit of an image problem. For example, in a recent review, several ...

What is Structured Illumination Microscopy? Structured Illumination Microscopy (SIM) is a super-resolution fluorescence microscopy technique that allows for imaging beyond the diffraction limit of ...

Nanoscopy is a field of microscopy that focuses on imaging and studying structures and processes at the nanoscale, typically below the diffraction limit of light. It encompasses various techniques ...