These iPS cells enabled the recapitulation of the disease in vitro; an impaired differentiation into the pituitary. The causal gene mutation was identified in the patient by exome sequencing analysis.

We were unable to process your request. Please try again later. If you continue to have this issue please contact [email protected]. Back to Healio The COVID-19 pandemic presents ...

Since 2005, the Cleveland Clinic Foundation has held an annual symposium addressing contemporary issues in pituitary disease. The faculty includes Cleveland Clinic Foundation staff, physicians and ...

Pituitary tumors exhibit a spectrum of biology, with variable growth and hormonal behaviors. They therefore provide an opportunity to examine pathogenetic mechanisms that underlie the neoplastic ...

>Successfully created the world's first model of pituitary disease using human iPS cells. >iPS cells were generated from a patient with CPH. These iPS cells enabled the recapitulation of the disease ...

Please provide your email address to receive an email when new articles are posted on . Most adults with free thyroxine levels slightly below the reference range have normal free T 4 index values and ...

Autoimmune involvement of the pituitary gland should be suspected in patients with AITD, particularly those for whom symptomatic relief is not achieved with thyroid hormone replacement alone Although ...

Many patients previously treated for pituitary tumours have chronic, multisystem morbidity in addition to hypopituitarism Many patients previously treated for pituitary tumours with visual-field ...

One in five adults may have a noncancerous tumor on their pituitary, a pea-sized gland in the brain that plays a central role in regulating the body’s hormones, according to research released Friday.

Chronic stress and elevated cortisol levels can damage the body's natural rhythm and disrupt the part of the brain involved ...

Researchers have developed the world's first congenital pituitary hypoplasia (CPH) model using patient-derived iPS cells. The research group succeeded in using the model to illuminate the mechanisms ...