Previously we showed that platelets accumulate in areas of low CBF 4h after brain ischemia. Similarly, CSER and CBF recovery after brain ischemia was enhanced in dogs treated with either prostacyclin ...

Colchicine is well known as an anti-inflammatory drug used in the treatment of acute gouty arthritis, familial Mediterranean fever and Behçet’s disease 1. Additionally, it has been used for the ...

Antiplatelet drugs are one of the main tools used to prevent thrombus formation in people who have had a heart attack or ...

New research led by a St. Michael's Hospital scientist reveals how platelets can inhibit inflammation and immune responses. The discovery, published in the journal Research, constitutes a fundamental ...

Researchers used mouse models and human blood to study LRP5. Inhibition reduced platelet aggregation and arterial thrombosis ...

A new study created a score to identify patients with platelet hyperreactivity and risk of related, future cardiovascular disease. Platelets are circulating cell fragments known to clump up and form ...

A simple blood test for platelet activity at middle age could one day help identify people at risk for Alzheimer's disease decades ahead of time, allowing for possible preventive therapy. The ...