Future Microbiol. 2013;8(1):73-84. Work in the Mulvey laboratory is supported by NIH grants AI095647, AI090369 and AI088086. TJ Wiles was funded by NIH Genetics Training Grant T32-GM007464. The ...

Pore-forming toxins (PFTs) produced by sea anemones, most notably the actinoporins, represent a fascinating class of proteins that disrupt target cell membranes through the formation of transmembrane ...

Pore-forming toxins are common bacterial poisons. They attack organisms by introducing holes in cell membranes. A team of scientists at the Technical University of Munich (TUM) has now unraveled the ...

Pore-forming toxins (PFTs) are a diverse class of proteins capable of disrupting cell membranes through the formation of transmembrane channels. These molecular machines play a central role in both ...

Pore-forming toxins are common bacterial poisons. They attack organisms by introducing holes in cell membranes. A team of scientists has now unraveled the mechanism of action for one of these toxins.

Biologists at the University of California, San Diego have discovered a new mechanism that allows cells to fight a class of toxins made by a wide variety of disease-causing bacteria. Their discovery, ...

Some types of bacteria have the ability to punch holes into other cells and kill them. They do this by releasing pore-forming toxins (PFTs) that latch onto the cell’s membrane and form a pore.

Pore-forming toxins are common bacterial poisons. They attack organisms by introducing holes in cell membranes. A team of scientists at the Technical University of Munich (TUM) has now unraveled the ...

Bacteria are becoming more resistant to the best weapon we have against them: antibiotics. But what if we could live together in peace? Instead of killing the germs, there may be a way to render them ...

Pore-forming proteins are found throughout nature. In humans, they play key roles in immune defense, while in bacteria they ...