Researchers have discovered how cells activate a last-resort DNA repair system when severe damage strikes. When genetic ...

This new review article highlights the pivotal and paradoxical role of R-loops in maintaining genomic stability while simultaneously posing risks to it. These three-stranded nucleic acid structures, ...

Breaks in our genetic code termed “DNA double-strand breaks” create cellular stress and cell death if not rapidly repaired. Environmental mutagens including UV light can cause DNA breaks, and these ...

“There are currently limited therapeutic options for elderly patients with myeloid malignancies, who are ineligible for stem cell transplantation,” commented Dr. Sayantani Sinha, a postdoctoral ...