The complement system, a key component of innate immunity, exerts profound influence on the initiation, progression and destabilisation of atherosclerotic plaques. Activation may proceed via the ...
The complement system, a central arm of innate immunity, comprises a network of plasma and membrane-bound proteins that detect and eliminate pathogens. In severe COVID-19, SARS-CoV-2 triggers ...
Among people with sickle cell disease—an inherited blood disorder—acute chest syndrome (ACS) is the leading cause of death. The condition is the result of red blood cells becoming stiff, sticky, and ...
K. pneumoniae is frequently the source of hospital-acquired infections and, due to the widespread use of antibiotics in these settings, has also acquired numerous resistance genes. In fact, over ...
Priority review for ravulizumab in IgA nephropathy could establish the first C5 complement inhibitor label in this indication, addressing substantial residual progression risk despite current standard ...
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