A small plane believed to be carrying just one person has disappeared hundreds of miles off the coast of San Diego.

San Diego sues Youtube, TikTok & other ‘Big Tech' for youth mental health crisis The lawsuit claims the social media companies use addictive techniques, similar to those used in slot machines ...

An image capturing the moment after a San Diego police officer shot a teen-age boy outside Santa Fe Depot. (Photo courtesy of San Diego Police Department via YouTube) The police shooting that left ...

Here's everything we know so far about the San Diego plane crash that killed Dave Shapiro and musician Daniel Williams.

Multiple people have been killed in San Diego after a small plane crashed into more than a dozen houses in foggy conditions as residents slept early Thursday.

A chaotic scene from a federal immigration raid on a popular San Diego restaurant is drawing new attention to government tactics in the push to fulfill President Trump's promise to deport millions ...

At least three people are dead and seven others, including two children, are missing after a "panga"-style fishing vessel washed ashore near San Diego on May 5, authorities said. Crews responded ...

San Diego City Attorney Heather Ferbert has filed a lawsuit against two federal agencies to protect $362 million already ...

SAN DIEGO (KUSI) — Since last year, rent rates increased by 4.1% in San Diego County and nearly 10% in the city of San Diego, according to a survey conducted by the Southern California Rental Housing ...

The crash comes weeks after a small Cessna crashed into a San Diego neighborhood in foggy weather and killed six people.

San Diego's 4-3 win over the Arizona Diamondbacks on Thursday night was the 20th one-run victory of the year for the Padres.

A small Cessna aircraft crashed in a San Diego military neighborhood Thursday morning setting several homes and vehicles on fire with multiple deaths reported.