Leaf senescence determines the duration of photosynthesis, nutrient remobilization efficiency, and ultimately crop yield and ...

Hair loss and graying, the earliest visible hallmarks of skin aging, result from the functional decline of hair follicle stem cells (HFSCs) and their niche. Dr. Zhao and colleagues conducted a ...

When there is insufficient TRF2, telomeres resemble a DNA break, activating the cascade of events that grind cell division to a halt. "Replicative senescence is a remarkably effective tumor suppressor ...

Demonstrates how dual-purpose therapeutic targets may address both hepatocellular carcinoma progression and cellular ...

NUDT21 regulates fibroblast senescence and is significantly decreased in aged and fibrotic lungs, impacting IPF progression. Alternative polyadenylation (APA) and NUDT21 downregulation enhance STAT3 ...

Demonstrates how dual-purpose therapeutic targets may address both hepatocellular carcinoma progression and cellular senescence ...

Here we propose the concept of infection-driven senescence (IDS) to describe the phenomenon in which microbial agents, beyond viruses, can trigger ...