If you are anything like us, whenever you plan a journey, you spend a remarkable amount of time thinking about the start and ...

Chromosomal instability (CIN) is pervasive in human tumours and often leads to structural or numerical chromosomal aberrations. Somatic structural variants (SVs) are intimately related to copy number ...

Using the Telomere-to-Telomere reference, we assemble the distribution of simple tandem repeat lengths present in the human genome. Analyzing over three hundred mammalian genomes, we find remarkable ...

Cells have evolved careful checks to ensure DNA is copied only once, but how they switch on replication at the right moment ...

Embryonic stem (ES) cells are pluripotent stem cells that can produce all cell types of an organism. ES cells proliferate rapidly and have been thought to experience high levels of intrinsic ...