Researchers have developed a cost-effective conversion that turns a standard epifluorescence microscope into a focus-stabilized TIRF platform achieving sub-10-nanometer DNA-PAINT and (d)STORM imaging.

News Medical talks to Samuel Penwell and Winfried Wiegraebe about how the Vutara VXL enables robust, high-throughput 3D super-resolution via single-molecule localization, pairing bi-plane detection ...

When single-molecule super-resolution microscopes were first commercialized some 15 years ago, they made headlines for their ability to resolve individual molecules and structures at the nanometer ...

Nanobodies are extremely small antibody fragments that bind to specific molecules. When nanobodies are labeled with dyes, ...

In a study published in Nature Methods on December 2, a research team led by Profs. Xu Tao and Ji Wei from the Institute of Biophysics of the Chinese Academy of Sciences has developed a ...

To unravel the complexities of biological phenomena, scientists have long relied on microscopy to visualize the intricate details of their specimens, including tissue architecture, cell morphology, ...

A single fluorophore sits on a glass coverslip, excited in sequence by four polarized beams optimized via a ...

The Aplo Scope is a new single-molecule super-resolution microscope designed for molecular imaging. The microscope combines imaging, laser control, and what the company describes as intuitive software ...

One method for visualizing dynamic biological processes is single particle tracking, a localization microscopy method. For this technique to be successful, several factors need to be considered, ...

Light field microscopy (LFM) is a revolutionary technique first introduced in 2006 which can essentially capture a 3D volume in a single snapshot, complete with digital refocusing and deconvolution.