Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) is a neurodegenerative disorder primarily caused by mutations in the SACS gene, which encodes the multifunctional protein sacsin.

Scientists have discovered a new cause of spastic ataxia, and believe this cause is also a trigger for other mitochondrial diseases – neurological disorders that can lead to serious coordination, ...

A research team from the Cell Structure and Dynamics Laboratory of the Biosystems and Integrative Sciences Institute (BioISI) of the Faculty of Sciences of the University of Lisbon (CIÊNCIAS) ...

Researchers have discovered the genetic cause of a rare disease reported only in patients originating from Newfoundland: Hereditary spastic ataxia. This condition is characterized by lower-limb ...

Spastic ataxia is a group of neurodegenerative disorders that rob victims of their abilities to walk and run. Barely able to sit, patients end up bound to wheelchairs. Brain scans reveal defects in a ...

This finding by researchers at Queen Mary, University of London and Montreal Neurological Institute and Hospital - The Neuro - at McGill University, is published in this week’s issue of the ...

What is causing this 55-year-old woman to have distorted speech and balance problems when walking, and why have her symptoms worsened progressively since they came on 14 years ago? Those are the ...

Spastic cerebral palsy is a disorder that involves muscle stiffness. Symptoms and signs may include difficulty walking, trouble manipulating objects, and vision, hearing, or speech challenges.